Effects of Individualized rTMS in DOC Patients

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 5, 2021

Primary Completion Date

December 31, 2024

Study Completion Date

March 31, 2025

Conditions
Disorder of ConsciousnessTranscranial Magnetic Stimulation
Interventions
DEVICE

individualized repetitive transcranial magnetic stimulation

During the rTMS-active stage, treatment will be given for 10 consecutive sessions (one session daily). The participants will be placed in the semi-reclining position on either a normal chair or a wheelchair and each stimulation session will last 20 minutes with a frequency of 10 Hz (train duration: 1s; inter-train interval: 5s; 200 effective stimulation series; 2000 pulses at 90% of RMT).

DEVICE

Sham repetitive transcranial magnetic stimulation

The sham coil will be used which has no magnetic field to send to the cerebral cortex while appearing to be the same shape as the active coil, with good approximation of auditory feedback.

Trial Locations (1)

510280

RECRUITING

Zhujiang Hospital of Southern Medical University, Guangzhou

All Listed Sponsors
lead

Qiuyou Xie

OTHER