Modulating Mechanisms in Patients With Chronic Subjective Tinnitus and/or Chronic Pain

NACompletedINTERVENTIONAL
Enrollment

135

Participants

Timeline

Start Date

December 21, 2021

Primary Completion Date

April 1, 2022

Study Completion Date

April 1, 2022

Conditions
TinnitusPain
Interventions
DIAGNOSTIC_TEST

Self-reported signs of central sensitization

Self-reported signs of central sensitization by means of the Central Sensitization Inventory (questionnaire)

DIAGNOSTIC_TEST

Objective signs of central sensitization

Objective signs of central sensitization by means of Quantitative Sensory Testing (mechanical and heat detection and pain thresholds, endogenous pain facilitation and inhibition)

DIAGNOSTIC_TEST

Audiological outcome measures (audiometry, tinnitus analysis, uncomfortable loudness) in tinnitus patients with and without pain

"* Audiometry Performance of pure tone audiometry according to the modified Hughson-Westlake method~* Tinnitus analysis Measurement of psychoacoustic features of tinnitus, including (1) tinnitus pitch, (2) loudness, (3) masking ability, and (4) residual inhibition.~* Uncomfortable Loudness measures Performance of Uncomfortable Loudness measurements to evaluate the presence of hyperacusis. ."

DIAGNOSTIC_TEST

Cognitive functioning

"Evaluation of cognitive functioning by means of:~* Auditory Stroop test~* Detecting letters task~* Letter-number sequencing task"

DIAGNOSTIC_TEST

Listening effort

Evaluation of listening effort by means of the modified version of the behavioral listening effort test based on a dual-task paradigm by Degeest, Keppler \& Corthals (2018) .

DIAGNOSTIC_TEST

Self-reported psychological factors

"Evaluation of psychological factors by means of:~* Depression, Anxiety and Stress Scale (DASS-21)~* Beck Depression Inventory (BDI)~* Big Five Inventory (BFI)~* Connor-Davidson Resilience Scale"

DIAGNOSTIC_TEST

Self-reported lifestyle factors

"Evaluation of lifestyle factors by means of:~Baecke Questionnaire Pittsburg Sleep Quality Index Insomnia Severity Index Stress subscale of the DASS 21"

DIAGNOSTIC_TEST

Self-reported measure of pain processing

Evaluation of self-reported pain processing by means of the Pain Catastrophizing Scale

DIAGNOSTIC_TEST

Self-reported quality of life

Self-reported quality of life by means of the SF-36 questionnaire

DIAGNOSTIC_TEST

Self-reported tinnitus severity and impact on daily life

Evaluation of self-reported tinnitus severity and impact on daily life by means of the Tinnitus Functional Index

DIAGNOSTIC_TEST

Self-reported hyperacusis

Evaluation of self-reported characteristics of hyperacusis by means of the Hyperacusis Questionnaire

DIAGNOSTIC_TEST

Self-reported tinnitus characteristics

Evaluation of self-reported tinnitus characteristics by means of the Tinnitus Sample Case History Questionnaire

DIAGNOSTIC_TEST

Self reported neck pain related disability

Evaluation of self-reported neck pain related disability using the Neck Disability Index

Trial Locations (1)

9000

Ghent University, Ghent

All Listed Sponsors
collaborator

Bijzonder onderzoeksfonds (BOF)

UNKNOWN

lead

University Ghent

OTHER

NCT05186259 - Modulating Mechanisms in Patients With Chronic Subjective Tinnitus and/or Chronic Pain | Biotech Hunter | Biotech Hunter