Niraparib with BeVAcizumab After Complete CytoreductioN in Patients with OvArian Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

390

Participants

Timeline

Start Date

February 1, 2022

Primary Completion Date

February 28, 2027

Study Completion Date

February 28, 2030

Conditions
Ovarian Cancer
Interventions
DRUG

Chemotherapy

Chemotherapy (carboplatin + paclitaxel) will be administred by intravenous infusion, AUC 5-6 q3w - 5 cycles during the treatment period

DRUG

Bevacizumab-Awwb

"MVASI (bevacizumab biosimilar) will be administrated by intravenous infusion at the second chemotherapy cycle for 5 cycles.~the administration will continue during maintenance phase. Total bevacizumab duration therapy is 15 months."

DRUG

Niraparib

niraparib will be administered orally once daily continuously after chemotherapy (+/- bevacizumab) cycles (maintenance treatment period). Total niraparib duration mainance treatment period is 2 years.

Trial Locations (87)

10003

RECRUITING

Hospital San Pedro de Alcantara, Cáceres

10408

RECRUITING

National Cancer Center, Seoul

11407

NOT_YET_RECRUITING

Hospital Universitario de Jerez, Jerez de la Frontera

13009

NOT_YET_RECRUITING

Institut Paoli Calmettes, Marseille

13915

NOT_YET_RECRUITING

Hôpital Nord Marseille, Marseille

14076

RECRUITING

Centre François Baclesse, Caen

15006

RECRUITING

Coruña University Hospital (CHUAC), A Coruña

15706

RECRUITING

CHU de Santiago de Compostela, Santiago de Compostela

20133

RECRUITING

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan

20141

RECRUITING

Istituto Europeo di Oncologia (IEO), Milan

20900

RECRUITING

Ospedale San Gerardo Monza, Monza

21000

NOT_YET_RECRUITING

CHU de Dijon - Bourgogne, Dijon

21079

NOT_YET_RECRUITING

Centre Georges François Leclerc, Dijon

22190

NOT_YET_RECRUITING

Centre CARIO - HPCA, Plérin

23100

NOT_YET_RECRUITING

Presidio Ospedaliero di Sondrio, Sondrio

25000

NOT_YET_RECRUITING

CHRU Besançon - Hôpital Jean Minjoz, Besançon

26000

NOT_YET_RECRUITING

CH Valence, Valence

28027

RECRUITING

Clínica Universidad de Navarra, Madrid

28046

NOT_YET_RECRUITING

Hospital Universitario La Paz, Madrid

28222

NOT_YET_RECRUITING

Hospital Universitario Puerta de Hierro, Madrid

29010

RECRUITING

Hospital Virgen de la Victoria, Málaga

29200

NOT_YET_RECRUITING

Hôpital Morvan CHRU de Brest, Brest

30029

NOT_YET_RECRUITING

Centre ONCOGARD - Institut de cancérologie du Gard, Nîmes

30120

RECRUITING

Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Murcia

31008

NOT_YET_RECRUITING

Clinica Universidad de Navarra., Pamplona

RECRUITING

Complejo Hospitalario de Navarra, Pamplona

31059

RECRUITING

Institut Claudius Regaud, Toulouse

33000

NOT_YET_RECRUITING

Clinique Tivoli-Ducos, Bordeaux

33011

RECRUITING

Hospital Universitario Central de Asturias, Oviedo

33076

NOT_YET_RECRUITING

Institut Bergonié, Bordeaux

34090

NOT_YET_RECRUITING

Institut régional du cancer de Montpellier, Montpellier

34295

NOT_YET_RECRUITING

CHU Montpellier - Hôpital Saint Eloi, Montpellier

35042

NOT_YET_RECRUITING

Centre Eugène Marquis, Rennes

37044

NOT_YET_RECRUITING

CHU Tours - Hôpital Bretonneau, Tours

38028

NOT_YET_RECRUITING

Groupe Hospitalier Mutualiste de Grenoble - Institut Daniel Hollard, Grenoble

38700

NOT_YET_RECRUITING

CHU Grenoble-Alpes - Site Nord (La Tronche), La Tronche

42055

NOT_YET_RECRUITING

CHU de Saint-Etienne - Pôle de Cancérologie, Saint-Priest-en-Jarez

44277

NOT_YET_RECRUITING

Hôpital Privé du Confluent, Nantes

44800

NOT_YET_RECRUITING

ICO - Centre René Gauducheau, Saint-Herblain

45100

NOT_YET_RECRUITING

CHR Orléans, Orléans

46010

RECRUITING

Fundación Investigación Clínico de Valencia., Valencia

49055

NOT_YET_RECRUITING

ICO Paul Papin, Angers

49300

NOT_YET_RECRUITING

Centre Hospitalier de Cholet, Cholet

50134

NOT_YET_RECRUITING

Firenze-Careggi, Florence

51100

NOT_YET_RECRUITING

Institut Jean Godinot, Reims

54000

NOT_YET_RECRUITING

ORACLE - Centre d'Oncologie de Gentilly, Nancy

59020

NOT_YET_RECRUITING

Centre Oscar Lambret, Lille

63011

NOT_YET_RECRUITING

Centre Jean Perrin, Clermont-Ferrand

67033

NOT_YET_RECRUITING

ICANS - Institut de cancérologie Strasbourg Europe, Strasbourg

69373

NOT_YET_RECRUITING

Centre Léon Bérard, Lyon

NOT_YET_RECRUITING

Hôpital Privé Jean Mermoz, Lyon

69495

RECRUITING

HCL - Centre Hospitalier Lyon Sud (Hospices Civils de Lyon), Pierre-Bénite

72000

NOT_YET_RECRUITING

Clinique Victor Hugo, Le Mans

75013

NOT_YET_RECRUITING

Groupe Hospitalier Pitié Salpêtrière, Paris

75014

NOT_YET_RECRUITING

Hôpital cochin, Paris

NOT_YET_RECRUITING

Hôpital Saint-Joseph, Paris

NOT_YET_RECRUITING

Institut Mutualiste Montsouris, Paris

75015

NOT_YET_RECRUITING

Hôpital Européen Georges Pompidou, Paris

75020

NOT_YET_RECRUITING

Groupe Hospitalier Diaconesses - Croix Saint-Simon, Paris

NOT_YET_RECRUITING

Hôpital Tenon, Paris

76038

NOT_YET_RECRUITING

Centre Henri Becquerel, Rouen

84918

NOT_YET_RECRUITING

Sainte Catherine Institut du cancer Avignon-Provence, Avignon

86021

NOT_YET_RECRUITING

CHU de Poitiers - Hôpital de la Milétrie, Poitiers

87042

NOT_YET_RECRUITING

CHU de Limoges - Hôpital Dupuytren, Limoges

94805

NOT_YET_RECRUITING

Gustave Roussy, Villejuif

119074

NOT_YET_RECRUITING

National University Hospital (NUH), Singapore

168583

NOT_YET_RECRUITING

National Cancer Centre Singapore, Singapore

Unknown

NOT_YET_RECRUITING

HCL - Groupe Hospitalier Est, Bron

NOT_YET_RECRUITING

HCL - Hôpital de la Croix Rousse, Lyon

06250

NOT_YET_RECRUITING

Centre Azuréen de Cancérologie, Mougins

135-8550

RECRUITING

Cancer Institute Hospital Of JFCR, Tokyo

277-8577

NOT_YET_RECRUITING

National Cancer Center Hospital East, Kashiwanoha

〒830-0011 6

RECRUITING

Kurume University Hospital Clinical Research Center, Kurume

305-8576

RECRUITING

University of Tsukuba Hospital, Tsukuba

951-8566

RECRUITING

Niigata Cancer Center Hospital, Niigata

700-8558

NOT_YET_RECRUITING

Okayama University Hospital, Kita-ku

〒329-0498 3311-1

NOT_YET_RECRUITING

Jichi Medical UH, Shimotsuke

791-0295

NOT_YET_RECRUITING

Ehime University Hospital, Ehime

990-9585

NOT_YET_RECRUITING

Yamagata University Hospital, Yamagata

350-1298

RECRUITING

Saitama Medical University International Medical Center, Saitama

06351

RECRUITING

Samsung Medical Center, Seoul

03080

RECRUITING

National University Hospital, Seoul

03722

RECRUITING

Severance Hospital, Seoul

05505

NOT_YET_RECRUITING

Asan Medical Center, Seoul

08003

RECRUITING

Hospital del Mar, Barcelona

08028

RECRUITING

Hospital Universitari Dexeus, Barcelona

08221

RECRUITING

Hospital Universitari MutuaTerrassa, Terrassa

All Listed Sponsors
lead

ARCAGY/ GINECO GROUP

OTHER