A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole

PHASE3RecruitingINTERVENTIONAL
Enrollment

220

Participants

Timeline

Start Date

August 3, 2022

Primary Completion Date

December 31, 2026

Study Completion Date

February 28, 2027

Conditions
Candidiasis, InvasiveCandidemia
Interventions
DRUG

SCY-078

Oral ibrexafungerp (SCY-078) as step-down therapy.

DRUG

Fluconazole

Oral fluconazole (SCY-078) as step-down therapy.

DRUG

Echinocandin

Intravenous echinocandin

Trial Locations (75)

1500

NOT_YET_RECRUITING

Lakeview Hospital, Benoni

1935

NOT_YET_RECRUITING

FCRN Clinical Trials Centre, Vereeniging

4400

NOT_YET_RECRUITING

Mediclinic Victoria, Tongaat

15260

NOT_YET_RECRUITING

University of Pittsburgh Medical Center, Pittsburgh

16132

NOT_YET_RECRUITING

IRCCS- University Hospital San Martino-IST, Genoa

19104

RECRUITING

University of Pennsylvania School of Medicine, Philadelphia

20162

NOT_YET_RECRUITING

Big Metropolitan Hospital Niguarda Regional Health Authority, Milan

21201

NOT_YET_RECRUITING

University of Maryland Medical Center, Baltimore

21287

NOT_YET_RECRUITING

Johns Hopkins Hospital, Baltimore

27710

RECRUITING

Duke University, Durham

30912

RECRUITING

Augusta University Medical Center, Augusta

41124

NOT_YET_RECRUITING

University Polyclinic Hospital of Modena, Modena

44093

NOT_YET_RECRUITING

Nantes University Hospital Center, Nantes

48109

RECRUITING

University of Michigan Hospital, Ann Arbor

48202

RECRUITING

Henry Ford Hospital, Detroit

50937

NOT_YET_RECRUITING

University Hospital Cologne, Cologne

55455

RECRUITING

University of Minnesota Medical Center, Minneapolis

55905

RECRUITING

Mayo Clinic - Rochester, Rochester

59701

NOT_YET_RECRUITING

Mercury Street Medical Group, PLLC, Butte

60596

NOT_YET_RECRUITING

Frankfurt University Clinic, Frankfurt

60637

RECRUITING

University of Chicago Medical Center, Chicago

63110

RECRUITING

Washington University School of Medicine, St Louis

70121

RECRUITING

University of Alabama at Birmingham School of Medicine, Birmingham

RECRUITING

Ochsner Medical Center, New Orleans

71103

NOT_YET_RECRUITING

LSU Health Sciences Center, Shreveport

77030

RECRUITING

University of Texas Health Science Center at Houston, Houston

RECRUITING

University of Texas MD Anderson Cancer Center, Houston

80291

RECRUITING

University of Colorado Anschutz Medical Campus, Denver

85719

NOT_YET_RECRUITING

Banner University Medical Center-Tucson, Tucson

95107

NOT_YET_RECRUITING

Victor Dupouy Hospital Center Argenteuil, Argenteuil

95817

RECRUITING

UC Davis Medical Center, Sacramento

98109

RECRUITING

Fred Hutchinson Cancer Research Center, Seattle

02903

WITHDRAWN

Rhode Island Hospital, Providence

02906

WITHDRAWN

The Miriam Hospital, Providence

Unknown

NOT_YET_RECRUITING

Saint Luc University Hospital, Brussels

NOT_YET_RECRUITING

University Hospital Ghent, Ghent

NOT_YET_RECRUITING

University Hospitals Leuven, Campus Gasthuisberg, Leuven

NOT_YET_RECRUITING

"University Multiprofile Hospital for Active Treatment Eurohospital Plovdiv, Plovdiv, Department of Surgery", Plovdiv

NOT_YET_RECRUITING

"University Multiprofile Hospital for Active Treatment and Emergency Medicine N.I. Pirogov, Sofia, Clinic of Purulent-Septic Surgery", Sofia

NOT_YET_RECRUITING

"University Multiprofile Hospital for Active Treatment Prof. Dr. Stoyan Kirkovich", Stara Zagora

NOT_YET_RECRUITING

Princess Margaret Hospital, Toronto

NOT_YET_RECRUITING

University Health Network- Toronto General Hospital, Toronto

NOT_YET_RECRUITING

Paris University Hospitals Center- Cochin Hospital, Paris

NOT_YET_RECRUITING

Saint-Louis Hospital, Paris

TERMINATED

University Hospital Center of Poitiers, Poitiers

NOT_YET_RECRUITING

University Hospital Freiburg, Freiburg im Breisgau

NOT_YET_RECRUITING

Univeristy Hospital Jena, Jena

TERMINATED

Municipal Hospital Munich GMbH/Hospital Neuperlach, Munich

NOT_YET_RECRUITING

Helios Clinic Wuppertal, Wuppertal

NOT_YET_RECRUITING

"General Hospital of Athens Evangelismos, 1st Department of Critical Care", Athens

NOT_YET_RECRUITING

"General Hospital of Athens Evangelismos", Athens

NOT_YET_RECRUITING

LAIKO General Hospital, Athens

NOT_YET_RECRUITING

"University General Hospital Attikon", Athens

NOT_YET_RECRUITING

"General Hospital of Thessaloniki Ippokratio", Thessaloniki

NOT_YET_RECRUITING

Lady Davis Carmel Medical Center, Infectious Diseases Unit, Haifa

NOT_YET_RECRUITING

Rambam Health Care Campus, Institute of Infectious Diseases, Haifa

NOT_YET_RECRUITING

Chaim Sheba Medical Center, Tel Litwinsky

NOT_YET_RECRUITING

Central Friuli University Healthcare Company, Udine

NOT_YET_RECRUITING

University of Pretoria and Steve Biko Academic Hospital, Pretoria

NOT_YET_RECRUITING

Keimyung University - Dongsan Medical Center, Daegu

NOT_YET_RECRUITING

CHA Bundang Medical Center, CHA University, Gyeonggi-do

NOT_YET_RECRUITING

Gangnam Severance Hospital, Seoul

NOT_YET_RECRUITING

Severance Hospital, Yonsei University Health System, Seoul

NOT_YET_RECRUITING

Wonju Severance Christian Hospital, Wŏnju

NOT_YET_RECRUITING

University Hospital Virgen Macarena, Seville

NOT_YET_RECRUITING

Hospital del Mar Medical Research Institute (IMIM), Barcelona

NOT_YET_RECRUITING

General University Hospital Gregorio Maranon, Madrid

NOT_YET_RECRUITING

University Hospital de La Princesa, Madrid

NOT_YET_RECRUITING

University Hospital Puerta de Hierro Majadahonda, Madrid

NOT_YET_RECRUITING

University and Polytechnic Hospital La Fe, Valencia

NOT_YET_RECRUITING

University Clinical Hospital of Valencia, Valencia

H4A 3J1

NOT_YET_RECRUITING

McGill University Health Centre, Montreal

0002

NOT_YET_RECRUITING

Netcare Jakaranda Hospital, Pretoria

NOT_YET_RECRUITING

Zuid-Afrikaans Hospital, Pretoria

0181

NOT_YET_RECRUITING

Life Groenkloof Hospital, Pretoria

All Listed Sponsors
lead

Scynexis, Inc.

INDUSTRY