IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

September 9, 2022

Primary Completion Date

January 30, 2026

Study Completion Date

February 1, 2026

Conditions
Nicotine Dependence
Interventions
DRUG

low dose Nicotine

IV nicotine infused over different delivery rates

DRUG

high dose Nicotine

IV Nicotine infused over different delivery rates

Trial Locations (1)

06516

RECRUITING

VA Healthcare System, West Haven

All Listed Sponsors
lead

Yale University

OTHER