60
Participants
Start Date
November 10, 2021
Primary Completion Date
January 5, 2022
Study Completion Date
January 5, 2022
PA9159 nasal spray solution, 10 μg one day treatment
Single dose of PA9159 (5 μg/nasal spray) is delivered intranasally through a metered-dose mechanical spray pump, one spray each in the left and right nostril.
PA9159 nasal spray solution, 20 μg one day treatment
Single dose of PA9159 (5 μg/nasal spray) is delivered intranasally through a metered-dose mechanical spray pump, two sprays each in the left and right nostril.
PA9159 nasal spray solution, 40 μg one day treatment
Single dose of PA9159 (10 μg/nasal spray) is delivered intranasally through a metered-dose mechanical spray pump, two sprays each in the left and right nostril.
PA9159 nasal spray solution, 80 μg one day treatment
Single dose of PA9159 (10 μg/nasal spray) is delivered intranasally through a metered-dose mechanical spray pump, four sprays each in the left and right nostril.
PA9159 nasal spray solution, 20 μg 7-day treatment
Repeated doses of PA9159 (5 μg/nasal spray) or Placebo is delivered intranasally through a metered-dose mechanical spray pump, two sprays each in the left and right nostril.
PA9159 nasal spray solution, 40 μg 7-day treatment
Repeated doses of PA9159 (10 μg/nasal spray) is delivered intranasally through a metered-dose mechanical spray pump, two sprays each in the left and right nostril.
Placebo, the same intranasal spray solution without PA9159 active ingredient
Placebo is delivered intranasally through a metered-dose mechanical spray pump with the same volume as the corresponding PA9159 dose group
Beijing TongRen Hospital, Beijing
Lead Sponsor
Anhui Palo Alto Pharmaceuticals, Inc.
INDUSTRY