Stellate Ganglion Block for PTSD

NARecruitingINTERVENTIONAL
Enrollment

360

Participants

Timeline

Start Date

November 17, 2022

Primary Completion Date

September 30, 2025

Study Completion Date

June 30, 2026

Conditions
Post-traumatic Stress Disorder
Interventions
PROCEDURE

Stellate Ganglion Block

After procedure informed consent, the procedure will be done using an ultrasound guided technique with a high frequency (6 to 13 MHz) linear transducer and confirmation of placement by fluoroscopy at sites who do this in clinical practice. The subject will be prepped and draped and placed in supine position in a suite with continuous vital sign monitoring and advanced cardiac life support equipment and IV placement. Local anesthesia with 1% buffered lidocaine will be achieved. After visualization of Chassaignac's tubercle of C6 is identified along with the carotid artery, internal jugular vein and longus colli and capitus muscles, a 25-gauge echo-enhanced needle will be inserted to inject anesthetic over 2 minutes anterior to the prevertebral fascia at the ventral aspect of the longus colli muscle, medial to Chassaignac's tubercle. The needle will be withdrawn and the subject will be monitored for a minimum of 30 minutes.

PROCEDURE

Sham Stellate Ganglion Block

"The Sham protocol is identical to the SGB protocol except After needle tip confirmation and negative aspiration, normal saline (0.9%) + contrast (unlabeled to keep treater blinded) will be slowly injected over 2 minutes while closely monitoring the subject."

Trial Locations (6)

33612

RECRUITING

James A. Haley Veterans' Hospital, Tampa, FL, Tampa

90822

ACTIVE_NOT_RECRUITING

VA Long Beach Healthcare System, Long Beach, CA, Long Beach

55417-2309

RECRUITING

Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis

84148-0001

RECRUITING

VA Salt Lake City Health Care System, Salt Lake City, UT, Salt Lake City

05001-3833

RECRUITING

White River Junction VA Medical Center, White River Junction, VT, White River Junction

53705-2254

RECRUITING

William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison

All Listed Sponsors
collaborator

Analydata, Inc.

INDUSTRY

lead

VA Office of Research and Development

FED