Evaluation of Endoscopic Surgical Field Clarity Using Hot Saline Versus Lactated Ringer's Irrigation

PHASE1CompletedINTERVENTIONAL
Enrollment

47

Participants

Timeline

Start Date

February 9, 2022

Primary Completion Date

June 13, 2024

Study Completion Date

June 13, 2024

Conditions
Irrigation
Interventions
DRUG

Lactated Ringer's Irrigation

Lactated Ringers at 40C will be used for the entirety of the surgery including the approach and exposure of the tumor as well as tumor resection, After surgery, two blinded skull base surgeon reviewers will rate the clarity of the endoscopic field of view at the recorded intervals. The surgical field will be graded using a widely accepted numeric integer (Boezaart) scale.

DRUG

Normal Saline

Normal Saline at 40C will be used for the entirety of the surgery including the approach and exposure of the tumor as well as tumor resection, After surgery, two blinded skull base surgeon reviewers will rate the clarity of the endoscopic field of view at the recorded intervals. The surgical field will be graded using a widely accepted numeric integer (Boezaart) scale.

Trial Locations (1)

15213

University of Pittsburgh Medical Center, Pittsburgh

All Listed Sponsors
lead

Carl Snyderman

OTHER