Serotonin Role on Brain Circuits Involved in Food Avoidance in Anorexia Nervosa

NARecruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

December 10, 2021

Primary Completion Date

July 31, 2025

Study Completion Date

August 31, 2025

Conditions
Anorexia Nervosa
Interventions
OTHER

PET imaging using [11C]DASB radioligand.

Subjects will be asked to complete a food choice task in PET/MRI. During the task, PET and MRI scans will be acquired simultaneously. This will allow us to see in real time during food choices the brain activations of the subjects. For imaging we will inject the DASB tracer intravenously. This radio ligand is a tracer that allows us to see the cerebral serotoninergic transmission by positron emission tomography.

BEHAVIORAL

Eye Tracker

"The second technique used is the eye tracker that will allow us to analyze food avoidance behaviors through the eyes. With a TOBII eye tracker we wil be able to follow the gaze of the subjects during the food preference task. It is a non-invasive approach."

Trial Locations (1)

42055

RECRUITING

CHU de Saint-Etienne, Saint-Etienne

All Listed Sponsors
lead

Centre Hospitalier Universitaire de Saint Etienne

OTHER