EXTENDed Antibiotic Durations Compared to Standard Durations for Patients With Complicated Intra-abdominal Infection.

PHASE3RecruitingINTERVENTIONAL
Enrollment

1,166

Participants

Timeline

Start Date

October 10, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Complicated Intra-abdominal Infection
Interventions
DRUG

Antibiotic - standard duration

Clinician decided antibiotic and duration of treatment

DRUG

Antibiotic - fixed-extended-duration

Clinician decided antibiotic for a fixed duration of 28 days.

Trial Locations (36)

Unknown

RECRUITING

Cwm Taf Morgannwg University Health Board,, Abercynon

RECRUITING

NHS Grampian, Aberdeen

RECRUITING

Hywel Dda University Health Board, Aberystwyth

RECRUITING

Buckinghamshire Healthcare NHS Trust, Aylesbury

RECRUITING

UniversityHospitals Birmingham NHS Foundation Trust, Birmingham

RECRUITING

Bolton NHS Foundation Trust, Bolton

RECRUITING

United Lincolnshire Hospitals NHS Trust - Pilgrim Hospital Boston, Boston

RECRUITING

University Hospitals Sussex NHS Foundation Trust, Brighton

NOT_YET_RECRUITING

North Bristol NHS Trust, Bristol

RECRUITING

North Cumbria Integrated Care NHS Foundation Turst, Carlisle

RECRUITING

Chesterfield Royal Hospital NHS Foundation Trust, Chesterfield

RECRUITING

University Hospital Coventry & Warwickshire, Coventry

RECRUITING

County Durham and Darlington NHS Foundation Trust, Darlington

RECRUITING

Northern Lincolnshire and Goole NHS Foundation Trust - Grimsby, Grimsby

RECRUITING

Hull University Teaching Hospitals NHS Trust, Hull

RECRUITING

East Suffolk and North Essex NHS Foundation Trust, Ipswich

RECRUITING

Leeds Teaching Hospitals NHS Trust, Leeds

RECRUITING

University Hospitals of Leicester NHS Trust, Leicester

RECRUITING

Chelsea and Westminster Hospital NHS Foundation Trust, London

RECRUITING

Guys and St Thomas' NHS Foundation Trust, London

RECRUITING

Imperial College Healthcare NHS Trust, London

RECRUITING

King'S College Hospital Nhs Foundation Trust, London

RECRUITING

East Cheshire NHS Trust, Macclesfield

RECRUITING

Manchester University NHS Foundation Trust, Manchester

ACTIVE_NOT_RECRUITING

Aneurin Bevan University Health Board, Newport

RECRUITING

Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich

RECRUITING

Nottingham University Hospital NHS Trust, Nottingham

RECRUITING

University Hospitals Plymouth NHS Trust, Plymouth

RECRUITING

Lancashire Teaching Hospitals NHS Foundation Trust, Preston

RECRUITING

Barking, Havering and Redbridge University Hospitals Nhs Trust, Romford

RECRUITING

East Sussex Hospitals NHS Trust, Saint Leonards-on-Sea

RECRUITING

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield

RECRUITING

North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees

RECRUITING

Sherwood Forest Hospitals NHS Foundation Trust, Sutton in Ashfield

RECRUITING

Royal Cornwall Hospitals NHS Trust, Truro

RECRUITING

University Hospitals Sussex NHS Foundation Trust, Worthing

All Listed Sponsors
collaborator

University of York

OTHER

collaborator

University of Birmingham

OTHER

collaborator

Chesterfield Royal Hospital NHS Foundation Trust

UNKNOWN

collaborator

University of Leeds

OTHER

collaborator

The Leeds Teaching Hospitals NHS Trust

OTHER

lead

Sarah Cockayne

OTHER