To Observe the Benefit of Adding Brachytherapy After CCRT on Resectable Esophageal Cancer Patients Without Surgery

NARecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

March 30, 2022

Primary Completion Date

June 18, 2025

Study Completion Date

June 18, 2025

Conditions
Esophageal Cancer
Interventions
RADIATION

Add-on Brachytherapy

Brachytherapy protocol starts within 2 weeks after consolidative EBRT, subjects who are enrolled will receive brachytherapy with specified balloon applicator. High-dose-rate (HDR) brachytherapy system will be used in the treatment, 5-Gy per fraction is delivered to the pre-treatment esophageal length of primary tumor(s), second treatment if applicable will be finished within 2 weeks after the first one, a total of 5-10Gy in 1-2 fractions will be delivered.

DEVICE

"BRAXX Esophageal Brachytherapy Applicator"

The device is intended for use with commercially available afterloader during brachytherapy. The purpose of the device is for delivery of radioactive source to the esophagus. This device is sterile, disposable and single-use.

Trial Locations (1)

33305

RECRUITING

Linkou Chang Gung Memorial Hospital, Taoyuan

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER