NCT05144295View on ClinicalTrials.gov

Lubiprostone for Functional Constipation in the Under 18 Years Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

274

Participants

Timeline

Start Date

January 1, 2022

Primary Completion Date

August 25, 2022

Study Completion Date

November 1, 2022

Conditions
Clinical EfficacyTreatment EfficacyDrug Side Effect
Interventions
DRUG

Lubiprostone Pill

Oral pills for constipation (Lubiprostone) will be given in a dose range from 24 mcg once daily to 24 mcg twice daily according to the participant weight.

DRUG

Lactulose Oral Liquid Product

"Lactulose Lactulose, or Duphalac syrup at a dose of 1 ml/kg once or twice daily (maximum 60 mL/day)"

DRUG

Bisacodyl 5 MG

Bisacodyl tablet (5 mg/tablet) in a dose of 2 tab/day for \< 12 years or 3 tab/day for \> 12 years

DRUG

Sodium Picosulfate

Sodium Picosulfate 0.75% drops in a daily dose of 2.5-20 mg/day

Trial Locations (2)

21521

Alexandria Main University Hospital, Alexandria

Faculty of Medicine, Alexandria

All Listed Sponsors
lead

Alexandria University

OTHER

NCT05144295 - Lubiprostone for Functional Constipation in the Under 18 Years Patients | Biotech Hunter | Biotech Hunter