1,276
Participants
Start Date
November 17, 2021
Primary Completion Date
January 31, 2027
Study Completion Date
April 30, 2027
Vasopressin; Methylprednisolone; Hydrocortisone
"Vasopressin, the vasoconstrictive hypophysal hormone, alone has not shown increased survival when compared to adrenaline. However, animal data have shown increased diastolic pressure, cerebral perfusion pressure and cerebral oxygenation in cardiac arrest treatment with vasopressin, and have when compared to adrenaline been associated with better cerebral blood flow.~Corticosteroids are currently used in septic shock treatment as a means to reduce time to shock reversal and thereby potentially improving mortality. Steroids have therefore also been suggested for cardiac arrest treatment. The potential role in resuscitation includes the catecholaminerg potentiation, vasoconstriction and protection from reperfusion injury."
Sodium chloride
Sodium chloride 9 mg/ml
RECRUITING
Sahlgrenska University Hospital, Gothenburg
RECRUITING
Tiohundra, Norrtälje
Sahlgrenska University Hospital
OTHER
Stockholm South General Hospital
OTHER
Tiohundra AB
INDUSTRY