NCT05139056View on ClinicalTrials.gov

Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas

PHASE1RecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

May 2, 2023

Primary Completion Date

August 7, 2026

Study Completion Date

August 7, 2026

Conditions
Currently Only Enrolling Glioblastoma Patients at First Recurrence
Interventions
BIOLOGICAL

Neural Stem Cells-expressing CRAd-S-pk7

Given intracerebrally

PROCEDURE

Resection

Undergo surgical resection

Trial Locations (4)

27109

NOT_YET_RECRUITING

Wake Forest University, Winston-Salem

60611

RECRUITING

Northwestern University, Chicago

91010

RECRUITING

City of Hope Medical Center, Duarte

94305

RECRUITING

Standford University, Stanford

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER