Effects of UCA-PSCs in Women With POF

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

December 1, 2018

Primary Completion Date

December 1, 2019

Study Completion Date

December 1, 2019

Conditions
Premature Ovarian Failure
Interventions
PROCEDURE

transplantation of human UCA-PSCs or WJ-MSCs into ovaries of POF patients

After vaginal sterilization, TVUS-guided transplantation was performed by the senior-level medical physician B Wang), using a SIEMENS ACUSON ANTANES premium edition system (SIEMENS AG Healthcae Sector, Erlangen, Germany), equipped with a 6-10 MHz probe. The solution (a total number of 2×10\^7cells, 1×10\^7 /400 μL for unilateral ovarian injection) was injected into the ovary by using 21G PTC needles (Hakko Medical Co, Japan) under TVUS guiance. Each patent received up to three transplantations.

Trial Locations (1)

210008

Reproductive Medicine Center, The affiliated Drum Towel Hospital of Nanjing University Medical School, Nanjing

All Listed Sponsors
lead

Li-jun Ding

OTHER

NCT05138367 - Effects of UCA-PSCs in Women With POF | Biotech Hunter | Biotech Hunter