COUREUR Study Myocardial Inflammation in Cyclist Part 2

NACompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

July 1, 2021

Primary Completion Date

July 5, 2021

Study Completion Date

October 1, 2023

Conditions
Myocardial Inflammation
Interventions
DIAGNOSTIC_TEST

cardiac MRI

"T1 and T2 relaxation times will be evaluated on basal and mid-cavity SA maps; a single ROI measurement in the septum will be manually drawn sufficiently far from tissue interfaces to avoid the impact of susceptibility artifacts from adjacent tissues. The differences in T1 and T2 relaxation times between rest and post-exercise will be analyzed.~Cardiac ventricular volumes, function and LV mass will also be quantified."

DIAGNOSTIC_TEST

Echocardiography

Measurements of mass, volumes and function will be obtained of both the left and right ventricles enabling comparisons with cardiac MRI and traditional echo measures.

DIAGNOSTIC_TEST

RootiRx for the ECG monitoring during the cycling ride

The final report will include the amount of recorded beats, the average heart rate, the maximum and minimum heart rate, the amount of cardiac pauses defined as an interruption in the ventricular rate \> 2 seconds. Reported atrial events include atrial ectopic beats and supraventricular tachycardia and ventricular events include ventricular ectopic beats, doublets, triplets, bigeminy, trigeminy and ventricular tachycardia.

DIAGNOSTIC_TEST

Blood sample

Blood sample will be performed 3 to 6 hours after the stage to analyze high-sensitivity cardiac Troponin T (high-sensitivity) levels, Creatine Phosphokinase (CPK) to eliminate the hypothesis of Troponin elevation induced by rhabdomyolysis and C-reactive Protein to corroborate the inflammatory aspect if there is any.

Trial Locations (2)

3500

Jessa Hospital, Hasselt

Unknown

Centre Hospitalier Universitaire de Nice, Nice

All Listed Sponsors
collaborator

Centre Hospitalier Universitaire de Nice

OTHER

lead

Jessa Hospital

OTHER