Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)

NARecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

August 30, 2022

Primary Completion Date

December 31, 2026

Study Completion Date

July 31, 2027

Conditions
DepressionHIV-1-infectionInflammation
Interventions
BEHAVIORAL

Cognitive-Behavioral Therapy for Adherence and Depression (CBT-AD)

CBT-AD is a behavioral intervention administered either in person or via Zoom. Each session lasts approximately 50 minutes. Participants will receive up to 12 individually delivered sessions over 4 months. Participants receive up to three individually delivered booster sessions through 6 months.

BEHAVIORAL

Antiretroviral Therapy (ART) Adherence Counseling

"This treatment involves a single session integrating CBT for depression with CBT for adherence following our Life-Steps approach."

Trial Locations (2)

33137

RECRUITING

Care Resource - Midtown Miami, Miami

33146

RECRUITING

University of Miami Neuroimaging Facility, Coral Gables

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Florida International University

OTHER