NCT05135091 - FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

June 16, 2022

Primary Completion Date

February 29, 2028

Study Completion Date

February 28, 2042

Conditions

Mesial Temporal Lobe Epilepsy

Interventions

BIOLOGICAL

NRTX-1001

Biological: NRTX-1001 is an experimental neural cell therapy product candidate derived from an allogeneic human embryonic stem cell line. The stem cells were converted into inhibitory nerve cells that produce GABA.

BIOLOGICAL

NRTX-1001

PROCEDURE

Sham Comparator

Trial Locations (30)

10016

RECRUITING

NYU Langone Comprehensive Epilepsy Center, New York

13210

RECRUITING

SUNY Upstate Medical University, Syracuse

19107

RECRUITING

Thomas Jefferson University Hospital, Philadelphia

27157

RECRUITING

Atrium Wake Forest Baptist, Winston-Salem

27710

RECRUITING

Duke University Hospital, Durham

28204

RECRUITING

Atrium Health, Charlotte

33136

RECRUITING

University of Miami, Miami

48201

RECRUITING

Wayne State University/Detroit Medical Center Comprehensive Epilepsy Program, Detroit

52242

RECRUITING

University of Iowa Health Care, Iowa City

53226

RECRUITING

Medical College of Wisconsin, Milwaukee

60612

RECRUITING

Rush University Medical Center, Chicago

60637

RECRUITING

University of Chicago, Chicago

68198

RECRUITING

University of Nebraska, Omaha

70121

RECRUITING

Ochsner Clinic Foundation, New Orleans

72205

RECRUITING

University of Arkansas for Medical Sciences, Little Rock

77030

RECRUITING

UTHealth Houston, Houston

80045

RECRUITING

University of Colorado Anschutz Medical Campus, Aurora

84108

RECRUITING

University of Utah Health, Salt Lake City

85054

RECRUITING

Mayo Clinic Arizona Epilepsy Center, Phoenix

90033

RECRUITING

University of Southern California Keck Hospital, Los Angeles

90095

RECRUITING

University of California Los Angeles, Los Angeles

92037

RECRUITING

University of California San Diego, San Diego

92868

RECRUITING

UC Irvine Medical Center, Orange

94143

RECRUITING

University of California San Francisco, San Francisco

94304

RECRUITING

Stanford University, Palo Alto

95817

RECRUITING

University of California Davis, Sacramento

97239

RECRUITING

Oregon Health and Science University, Portland

98104

RECRUITING

University of Washington Regional Epilepsy Center, Seattle

85724-5023

RECRUITING

Banner-University of Arizona Medical Center Tucson Comprehensive Epilepsy Program, Tucson

02215

RECRUITING

Beth Israel Deaconess Medical Center, Boston