Auricular Vagal Stimulation in Alcohol Craving

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2018

Primary Completion Date

January 31, 2019

Study Completion Date

February 1, 2019

Conditions
Alcohol WithdrawalPsychophysiologic Reaction
Interventions
DEVICE

auriStim, for auricular vagal stimulation

For auricular vagal stimulation we used auriStim (AU0115, Multisana GmbH, Vienna, Austria). Using a green light-emitting diode (LEDs) flashlight, blood vessels in the cymba conchae of the left ear side were detected. Minimal invasive needles (penetrating 1-2mm) were placed close to the vessel-bifurcation to provide efficient stimulation of the auricular branch of the vagus nerve. The built-in microchip controls monophasic volt pulses of 1 ms, with alternating polarity, a frequency of 1 Hz and an amplitude of 4V. Stimulation lasted for 72h in total with alternating on/off periods of three hours. Thereafter, the device was removed, and patients continued their therapy consisting of anti-withdrawal medication.

Trial Locations (1)

1090

Medical University of Vienna, Department of Psychiatry and Psychotherapy, Vienna

All Listed Sponsors
lead

Medical University of Vienna

OTHER

NCT05131334 - Auricular Vagal Stimulation in Alcohol Craving | Biotech Hunter | Biotech Hunter