Dapsone Use in Patients With Aneurysmal Subarachnoid Hemorrhage.

PHASE3CompletedINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

September 5, 2007

Primary Completion Date

December 7, 2008

Study Completion Date

March 10, 2009

Conditions
Subarachnoid HemorrhageBrain IschemiaSubarachnoid Hemorrhage, AneurysmalAneurysmal Subarachnoid HemorrhageDelayed Cerebral IschemiaVasospasm, Cerebral
Interventions
DRUG

Dapsone

Dapsone is a drug that has been used clinically for several decades due to its anti-infective effect. It has an anti-inflammatory effect due to its inhibitory action on neutrophils. Neuroprotective effects have been found experimentally with the use of dapsone, predominantly through its glutamate receptors antagonistic effect; these are the main receptors involved in neuronal excitotoxicity.

DRUG

Aluminum Hydroxide Gel

Aluminum Hydroxide Gel is an antacid that works quickly to lower the acid in the stomach

Trial Locations (1)

14269

El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City

All Listed Sponsors
lead

El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez

OTHER

NCT05131295 - Dapsone Use in Patients With Aneurysmal Subarachnoid Hemorrhage. | Biotech Hunter | Biotech Hunter