Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy

PHASE2RecruitingINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

February 15, 2023

Primary Completion Date

January 31, 2027

Study Completion Date

December 31, 2027

Conditions
Ototoxic Hearing Loss
Interventions
DRUG

Sodium Thiosulfate + Mannitol

Drug delivery will be sequential, where Mannitol will be infused over 30 minutes and Sodium Thiosulfate will be infused over 15 minutes.

Trial Locations (1)

Unknown

RECRUITING

Sunnybrook Health Sciences Centre, Toronto

All Listed Sponsors
lead

Sunnybrook Health Sciences Centre

OTHER