31
Participants
Start Date
January 6, 2022
Primary Completion Date
January 6, 2027
Study Completion Date
January 6, 2027
Allogenic transplantation
"1. Conditioning regimen Fludarabine (30mg/m2/day i.v: day -6 to day -2), pre-transplant cyclophosphamide (14.5 mg/kg/day i.v: day -6 and day -5), and Total Body Irradiation (2 Gray on day-1)~2. Stem cell source Bone Marrow~3. GVHD Prophylaxis Rabbit ATG dosed at 0.5 mg/kg on day -9 and 2 mg/kg on days -8 and -7, Cyclophosphamide 50 mg/Kg/day at D+3 and D+4, Tacrolimus (residual 8-12 microg/L) and mycophenolate (MMF) from D+5. In absence of GvHD, MMF will be stopped at D35 and tacrolimus at day 365.~4. Prevention of EBV reactivation Rituximab 150mg/m2 intravenously at Day+5 post HSCT, Each infusion of Rituximab will be preceded by administration of anti-pyretic and an antihistaminic, e.g. paracetamol and diphenhydramine."
RECRUITING
CHU Amiens, Amiens
RECRUITING
CHU Angers, Angers
RECRUITING
CHU Besancon, Besançon
RECRUITING
CHU Bordeaux, Bordeaux
RECRUITING
Hôpital du Haut-Lévêque, Bordeaux
RECRUITING
CHU Caen, Caen
RECRUITING
Hopital Percy, Clamart
RECRUITING
CHU Clermont, Clermont-Ferrand
RECRUITING
CHU-Estaing_Clermont Ferrand, Clermont-Ferrand
RECRUITING
Henri Mondor, Créteil
RECRUITING
CHU Grenoble, Grenoble
RECRUITING
CHU Lille, Lille
RECRUITING
CHU Lille, Lille
RECRUITING
CHU Limoges, Limoges
RECRUITING
CHU Lyon Sud, Lyon
RECRUITING
IHOP, CHU Lyon, Lyon
RECRUITING
Hopital La Timone, Marseille
RECRUITING
CHU Montpellier, Montpellier
RECRUITING
CHU Montpellier, Montpellier
RECRUITING
CHU Nancy, Nancy
RECRUITING
CHU Nantes, Nantes
RECRUITING
CHU Nantes, Nantes
RECRUITING
CHU Nice, Nice
RECRUITING
Hopital Necker, Paris
RECRUITING
Hopital Robert Debré, Paris
RECRUITING
Hôpital de La Pitié Salpetriere, Paris
RECRUITING
Hôpital Saint Antoine, Paris
RECRUITING
Hôpital Saint Louis, Paris
RECRUITING
CHU Poitiers, Poitiers
RECRUITING
CHU Rennes, Rennes
RECRUITING
CHU Rennes, Rennes
RECRUITING
Crlcc Henri Becquerel Rouen, Rouen
RECRUITING
ICLN_Saint Priest En Jarez, Saint-Priest-en-Jarez
RECRUITING
CHRU Strasbourg, Strasbourg
RECRUITING
CHU Toulouse, Toulouse
Assistance Publique - Hôpitaux de Paris
OTHER