NCT05126277View on ClinicalTrials.gov

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

PHASE3RecruitingINTERVENTIONAL
Enrollment

420

Participants

Timeline

Start Date

July 14, 2022

Primary Completion Date

June 22, 2027

Study Completion Date

November 5, 2030

Conditions
Lupus Nephritis
Interventions
DRUG

ianalumab s.c. q4w

ianalumab s.c. q4w in addition to SoC

DRUG

ianalumab s.c. q12w

ianalumab s.c. q12w in addition to SoC

DRUG

placebo s.c.

placebo s.c. q4w in addition to SoC

Trial Locations (188)

1426

RECRUITING

Novartis Investigative Site, Buenos Aires

4000

RECRUITING

Novartis Investigative Site, San Miguel de Tucumán

4032

RECRUITING

Novartis Investigative Site, Debrecen

7400

RECRUITING

Novartis Investigative Site, Kaposvár

9001

RECRUITING

Novartis Investigative Site, Quetzaltenango

10021

RECRUITING

Hospital for Special Surgery, New York

10028

RECRUITING

Northwell Health, New York

10117

RECRUITING

Novartis Investigative Site, Tallinn

10138

RECRUITING

Novartis Investigative Site, Tallinn

10154

RECRUITING

Novartis Investigative Site, Torino

10330

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Bangkok

10400

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Bangkok

10468

RECRUITING

James J Peters VA Medical Center, The Bronx

10700

RECRUITING

Novartis Investigative Site, Bangkok

11217

RECRUITING

Novartis Investigative Site, Taipei

12065

RECRUITING

NY Nephrology, Clifton Park

13385

RECRUITING

Novartis Investigative Site, Marseille

13620

RECRUITING

Novartis Investigative Site, Bundang Gu

14127

RECRUITING

Circuit Clinical, Orchard Park

15706

RECRUITING

Novartis Investigative Site, Santiago de Compostela

16499

RECRUITING

Novartis Investigative Site, Suwon

19104

RECRUITING

Univ of Pennsylvania Medical Center, Philadelphia

20132

RECRUITING

Novartis Investigative Site, Milan

20400

RECRUITING

Novartis Investigative Site, Kuala Terengganu

22033

RECRUITING

Northern Assoc of Northern VA, Fairfax

25030

RECRUITING

Novartis Investigative Site, Besançon

27100

RECRUITING

Novartis Investigative Site, Pavia

27103

WITHDRAWN

Brookview Hills Research Assoc, Winston-Salem

28040

RECRUITING

Novartis Investigative Site, Madrid

28041

RECRUITING

Novartis Investigative Site, Madrid

30044

RECRUITING

Parris and Associates Rheumatology, Lawrenceville

30120

WITHDRAWN

Novartis Investigative Site, El Palmar

30303

RECRUITING

Emory University School of Medicine, Atlanta

30342

RECRUITING

Fides Clinical Research, Atlanta

31008

RECRUITING

Novartis Investigative Site, Pamplona

31054

RECRUITING

Novartis Investigative Site, Toulouse

32224

RECRUITING

Mayo Clinic Jacksonville, Jacksonville

33076

RECRUITING

Novartis Investigative Site, Bordeaux

33100

RECRUITING

Novartis Investigative Site, Udine

33136

RECRUITING

University Of Miami, Miami

35015

WITHDRAWN

Novartis Investigative Site, Daejeon

35294

RECRUITING

University Of Alabama, Birmingham

36214

RECRUITING

Novartis Investigative Site, Vigo

37160

RECRUITING

Novartis Investigative Site, León

38043

RECRUITING

Novartis Investigative Site, Grenoble

38320

RECRUITING

Novartis Investigative Site, San Cristóbal de La Laguna

40447

RECRUITING

Novartis Investigative Site, Taichung

44791

RECRUITING

Novartis Investigative Site, Bochum

45267

RECRUITING

University Of Cincinnati, Cincinnati

46017

RECRUITING

Novartis Investigative Site, Valencia

48149

RECRUITING

Novartis Investigative Site, Münster

48201

RECRUITING

Wayne State University, Detroit

49933

WITHDRAWN

Novartis Investigative Site, Angers

50134

RECRUITING

Novartis Investigative Site, Florence

50200

RECRUITING

Novartis Investigative Site, Chiang Mai

50586

RECRUITING

Novartis Investigative Site, Kuala Lumpur

52074

RECRUITING

Novartis Investigative Site, Aachen

53792

RECRUITING

Uni Wisconsin School Med Pub Health, Madison

54511

RECRUITING

Novartis Investigative Site, Vandœuvre-lès-Nancy

61469

RECRUITING

Novartis Investigative Site, Gwangju

64440

RECRUITING

Novartis Investigative Site, Monterrey

66160

RECRUITING

University of Kansas Hospital, Kansas City

68020

RECRUITING

Novartis Investigative Site, Oaxaca City

69003

RECRUITING

Novartis Investigative Site, Lyon

70112

RECRUITING

UMC New Orleans, New Orleans

70601

RECRUITING

Accurate Clinical Research, Lake Charles

71122

RECRUITING

Novartis Investigative Site, Foggia

75013

RECRUITING

Arthritis and Rheumatology Ins, Allen

75230

RECRUITING

Liberty Research Center, Dallas

75235

RECRUITING

Univof Texas Southwestern Med Cntr, Dallas

76000

WITHDRAWN

Novartis Investigative Site, Querétaro

76034

RECRUITING

Precision Comprehensive Research, Colleyville

76070

RECRUITING

Novartis Investigative Site, Querétaro

76502

RECRUITING

Baylor Scott and White Research, Temple

78229

RECRUITING

Uni of Texas Health Science Center, San Antonio

80131

WITHDRAWN

Novartis Investigative Site, Napoli

83301

RECRUITING

Novartis Investigative Site, Kaohsiung City

86021

RECRUITING

Novartis Investigative Site, Poitiers

87108

RECRUITING

VA NM Healthcare System, Albuquerque

89102

RECRUITING

Univ of Nevada School of Med, Las Vegas

90048

WITHDRAWN

Wallace Rheumatic Study Center, Los Angeles

90095

RECRUITING

University of California LA, Los Angeles

90110

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Songkhla

90623

RECRUITING

Advanced Medical Research, La Palma

92037

RECRUITING

University of California San Diego, San Diego

92111

RECRUITING

Kaiser Permanente, San Diego

92868

RECRUITING

University of California Irvine, Orange

93053

WITHDRAWN

Novartis Investigative Site, Regensburg

95817

RECRUITING

UC Davis School of Medicine, Sacramento

96000

RECRUITING

Novartis Investigative Site, Sibu

100000

RECRUITING

Novartis Investigative Site, Hanoi

100034

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Beijing

110003

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Shenyang

110111

RECRUITING

Novartis Investigative Site, Bogota

130041

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Changchun

169608

RECRUITING

Novartis Investigative Site, Singapore

200040

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Shanghai

200080

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Shanghai

200127

COMPLETED

Novartis Investigative Site, Shanghai

210029

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Nanjing

226014

RECRUITING

Novartis Investigative Site, Lucknow

230022

WITHDRAWN

Novartis Investigative Site, Hefei

240672

WITHDRAWN

Novartis Investigative Site, Râmnicu Vâlcea

256603

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Binzhou

276000

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Linyi

280796

RECRUITING

Novartis Investigative Site, Madrid

300736

RECRUITING

Novartis Investigative Site, Timișoara

315016

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Zhejiang

330006

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Nanchang

400006

RECRUITING

Novartis Investigative Site, Cluj-Napoca

400038

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Chongqing

407219

RECRUITING

Novartis Investigative Site, Taichung

410008

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Changsha

410619

RECRUITING

Novartis Investigative Site, Oradea

430022

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Wuhan

430060

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Wuhan

500003

RECRUITING

Novartis Investigative Site, Secunderabad

510000

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Guangzhou

510080

COMPLETED

Novartis Investigative Site, Guangzhou

COMPLETED

Novartis Investigative Site, Guangzhou

510120

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Guangzhou

510280

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Guangzhou

515041

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Shantou

518020

WITHDRAWN

Novartis Investigative Site, Shenzhen

518037

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Shenzhen

545005

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Liuzhou

570311

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Haikou

610041

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Chengdu

700000

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Ho Chi Minh City

710004

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Xian

999077

RECRUITING

Novartis Investigative Site, Tuenmen

4790084

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Temuco

7500922

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Santiago

07764

RECRUITING

Sahni Rheumatology and Therapy, West Long Branch

77555-0144

WITHDRAWN

University of Texas Medical Branch, Galveston

C1056ABJ

RECRUITING

Novartis Investigative Site, CABA

B1900AWT

RECRUITING

Novartis Investigative Site, La Plata

C1015ABO

RECRUITING

Novartis Investigative Site, Buenos Aires

C1119ACN

WITHDRAWN

Novartis Investigative Site, Buenos Aires

29055 450

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Vitória

40150 150

RECRUITING

Novartis Investigative Site, Salvador

65020-600

WITHDRAWN

Novartis Investigative Site, São Luís

30150-221

RECRUITING

Novartis Investigative Site, Belo Horizonte

36010 570

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Juiz de Fora

80440-020

WITHDRAWN

Novartis Investigative Site, Curitiba

50740-900

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Recife

90035-003

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Porto Alegre

90035-074

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Porto Alegre

09090-790

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Santo André

40301-155

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Salvador

T2N 4Z6

RECRUITING

Novartis Investigative Site, Calgary

V5Z 1L7

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Vancouver

R3A 1R9

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Winnipeg

M9W 6V1

RECRUITING

Novartis Investigative Site, Etobicoke

N6A 5W9

RECRUITING

Novartis Investigative Site, London

M5T 2S8

RECRUITING

Novartis Investigative Site, Toronto

H1T 2M4

RECRUITING

Novartis Investigative Site, Montreal

J1G 2E8

RECRUITING

Novartis Investigative Site, Sherbrooke

050001

RECRUITING

Novartis Investigative Site, Medellín

080020

RECRUITING

Novartis Investigative Site, Barranquilla

RECRUITING

Novartis Investigative Site, Barranquilla

779 00

RECRUITING

Novartis Investigative Site, Olomouc

128 00

RECRUITING

Novartis Investigative Site, Prague

01010

RECRUITING

Novartis Investigative Site, Guatemala City

01011

RECRUITING

Novartis Investigative Site, Guatemala City

Unknown

RECRUITING

Novartis Investigative Site, Kwun Tong

H-1032

RECRUITING

Novartis Investigative Site, Budapest

H-1097

RECRUITING

Novartis Investigative Site, Budapest

560 079

RECRUITING

Novartis Investigative Site, Bangalore

160 012

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Chandigarh

09134

WITHDRAWN

Novartis Investigative Site, Cagliari

00168

RECRUITING

Novartis Investigative Site, Roma

LT 50161

RECRUITING

Novartis Investigative Site, Kaunas

LT-08661

RECRUITING

Novartis Investigative Site, Vilnius

011172

RECRUITING

Novartis Investigative Site, Bucharest

022328

RECRUITING

Novartis Investigative Site, Bucharest

S308433

RECRUITING

Novartis Investigative Site, Singapore

602 715

RECRUITING

Novartis Investigative Site, Busan

705 718

WITHDRAWN

Novartis Investigative Site, Daegu

03722

RECRUITING

Novartis Investigative Site, Seoul

04763

RECRUITING

Novartis Investigative Site, Seoul

05030

WITHDRAWN

Novartis Investigative Site, Seoul

05505

RECRUITING

Novartis Investigative Site, Seoul

06591

RECRUITING

Novartis Investigative Site, Seoul

08003

RECRUITING

Novartis Investigative Site, Barcelona

08035

RECRUITING

Novartis Investigative Site, Barcelona

BD9 6RJ

RECRUITING

Novartis Investigative Site, Bradford

SE1 9RT

RECRUITING

Novartis Investigative Site, London

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY