Gut Kidney Axis in Enteric Hyperoxaluria

NARecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

November 10, 2022

Primary Completion Date

March 1, 2026

Study Completion Date

March 1, 2026

Conditions
Enteric Hyperoxaluria
Interventions
OTHER

Moderately High Oxalate (MOx) Diet

Diets will contain 16% protein, 30% fat, and 54% carbohydrate, and are controlled in the amounts of calcium (400mg), oxalate (250mg), ascorbic acid (50mg), fiber (30 grams) and, other nutrients. Each controlled diet will be consumed for four days. On days of controlled diets, subjects will be provided with 2 liters of bottled water per day to ensure adequate hydration. After the controlled diet period, there will be a three-day washout period, where participants will consume Ad-lib diets supplemented with a daily intake of oxalate in the form of cooked spinach to be taken with breakfast daily for a total of 2 weeks.

Trial Locations (1)

10016

RECRUITING

NYU Langone Health, New York

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

NYU Langone Health

OTHER