NCT05110144 - Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 1, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions

Refractory Chronic Cough

Interventions

DRUG

Duloxetine 30 MG

30mg orally for 4 weeks

DRUG

Duloxetine 60 MG

60mg orally for 4 weeks

DRUG

Amitriptyline 25 MG

25 mg orally for 4 weeks

DRUG

Amitriptyline 50 MG

50 mg orally for 4 weeks

DRUG

Placebo 30 MG

30mg tablet with no active study ingredient for 4 weeks

DRUG

Placebo 60 MG

60mg tablet with no active study ingredient for 4 weeks

Trial Locations (1)

RECRUITING

Mayo Clinic in Rochester, Rochester