NCT05108870View on ClinicalTrials.gov

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

98

Participants

Timeline

Start Date

July 17, 2024

Primary Completion Date

January 1, 2026

Study Completion Date

January 1, 2026

Conditions
Human Papilloma VirusHPVHPV Positive Oropharyngeal Squamous Cell CarcinomaHead and Neck Cancer
Interventions
DRUG

HB-201

A anti-cancer vaccine that treats HPV-related cancers.

DRUG

HB-202

A anti-cancer vaccine that treats HPV-related cancers.

DRUG

Carboplatin

Chemotherapy drug.

DRUG

Paclitaxel

Chemotherapy drug.

PROCEDURE

Transoral Robotic Surgery

Transoral robotic surgery is a procedure to remove mouth and throat cancers in which a surgeon uses a sophisticated, computer-enhanced system to guide the surgical tools.

Trial Locations (1)

60637

RECRUITING

University of Chicago, Chicago

All Listed Sponsors
lead

University of Chicago

OTHER