Effects of Pioglitazone on Stress Reactivity and Alcohol Craving

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

May 12, 2022

Primary Completion Date

August 16, 2024

Study Completion Date

August 16, 2024

Conditions
Alcohol Use Disorder
Interventions
DRUG

Pioglitazone

For the current trial we will follow recommended adult initial dosing at 30 mg/d to reach maintenance dose of 45 mg/d by end of week 1, which is within standard titration parameters as per the investigator's brochure.

DRUG

Placebo

Pill capsules will look same as that of active drug.

Trial Locations (1)

77030

The University of Texas Health Science Center of Houston, Houston

All Listed Sponsors
collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

The University of Texas Health Science Center, Houston

OTHER