Effect of Antibiotic Choice On ReNal Outcomes (ACORN)

PHASE4CompletedINTERVENTIONAL
Enrollment

2,634

Participants

Timeline

Start Date

November 10, 2021

Primary Completion Date

October 21, 2022

Study Completion Date

October 21, 2022

Conditions
SepsisAKINeurotoxicity
Interventions
DRUG

anti-pseudomonal cephalosporin

Providers will be prompted to order an anti-pseudomonal cephalosporin, such as cefepime with a dose range of 500 mg, 1,000 mg, or 2,000 mg, and frequency every 6, 8, 12, or 24 hours based on provider discretion.

DRUG

anti-pseudomonal penicillin

Providers will be prompted to order anti-pseudomonal penicillin, such as piperacillin-tazobactam with a dose range of 3.375 g or 4.5 g and frequency every 6, 8, or 12 hours based on provider discretion.

Trial Locations (1)

37232

Vanderbilt University Medical Center, Nashville

All Listed Sponsors
lead

Vanderbilt University Medical Center

OTHER

NCT05094154 - Effect of Antibiotic Choice On ReNal Outcomes (ACORN) | Biotech Hunter | Biotech Hunter