600
Participants
Start Date
June 1, 2017
Primary Completion Date
March 1, 2024
Study Completion Date
December 30, 2025
Trancatheter Edge to Edge Repair
TEER is performed by apposing the edges of the anterior and posterior leaflet (edge-to-edge) of prolapsed MV. The patient may be under conscious sedation or general anesthesia, depending on hospital standard practice. The procedure is performed through femoral venous access and the inter-atrial septum is crossed using standard techniques. Trans-septal puncture allows MitraClip Steerable Guide Catheter (Guide) to advance so that the guide is positioned over the mitral valve. The MitraClip delivery catheter is advanced to the MitraClip device and emerges from the tip of the guide into the left atrium. The MitraClip device can now be opened and advanced through the MV in the LV. Once in the LV, it is pulled back to grasp the leaflets. Two-dimensional and/or 3-dimensional echocardiography and color Doppler are useful for evaluating the anatomical features of the mitral valve and directing the procedure until the double orifice is formed alongside evaluating residual mitral regurgitation
Mitral Valve Replacement
Mitral valve replacement is performed using mechanical or biological prosthesis while preserving the subvalvular apparatus to avoid dilation of the left ventricle over time.
Restrictive Mitral Annuloplastie
Mitral valve repair consists of a restrictive mitral annuloplasty (RMA) using a prosthetic ring
Restrictive Mitral Annuloplastie/Subvalvular Repair
RMA may be associated with the use of a subvalvular repair (SR). The SR permits the approximation or the relocation of papillary muscles which is displaced by post infarction scar formation.
Francesco Nappi, Saint-Denis
Centre Cardiologique Du Nord, Saint-Denis
Campus Bio-Medico University
OTHER
Henri Mondor University Hospital
OTHER
Hokkaido University
OTHER
University of Genova
OTHER
Centre Cardiologique du Nord
OTHER