21
Participants
Start Date
May 13, 2022
Primary Completion Date
January 27, 2024
Study Completion Date
January 27, 2024
Aerobic and resistance training 12 week exercise programme
See arm/group description
Venous blood sampling
full blood count, urea \& electrolytes, C-reactive protein, coagulation screen, liver function tests, erythrocyte sedimentation rate.
Muscle Ultrasound
Ultrasound of vastus lateralis to ascertain muscle structure (thickness, pennation angle and fascicle length)
Cardiopulmonary exercise testing (CPET)
The assessment of anaerobic threshold as a measure of changes in aerobic function between the two groups will be assessed using CPET
Quality of life questionnaire completion
The use of validated questionnaires to assess quality of life parameters; Duke Activity Status Index (DASI), EORTC-QLQ C30 (quality of life for cancer patients) and the International Physical Activity Questionnaire (IPAQ).
University of Nottingham, Royal Derby Hospital, Derby
University Hospitals of Derby and Burton NHS Foundation Trust
OTHER
University of Nottingham
OTHER