62
Participants
Start Date
January 1, 2017
Primary Completion Date
August 30, 2020
Study Completion Date
June 30, 2021
Anaerobically Cultivated Human Intestinal Microbiota (ACHIM)
One vial of ACHIM suspension (ACHIM Biotherapeutics AB, Vallingby, Sweden), containing 30 x 109 colony forming unit (CFU) of bacteria, was given through the work channel of a gastroscope into the lower part of duodenum.
Donor fecal microbiota transplantation
Only 60 ml of sterile 0.9% normal saline were added to a stool specimen, collected from the respective donor, with a weight of \~30 g and homogenized manually. Then 60 ml of feces-suspension (screened from the patients view) were instilled through the work channel of a gastroscope into the lower part of the duodenum.
Placebo
Only 60 ml of sterile 0.9% normal saline were added to the patient's own stool specimen with a weight of \~30 g and homogenized manually. Then 60 ml of feces-suspension (screened from the patients view) were instilled through the work channel of a gastroscope into the lower part of the duodenum.
Haukeland Unversity Hospital, Bergen
Haukeland University Hospital
OTHER