Fecal Microbiota Transplantation and ACHIM for Manipulating Gut Microbiota in IBS Patients

NACompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

January 1, 2017

Primary Completion Date

August 30, 2020

Study Completion Date

June 30, 2021

Conditions
Irritable Bowel SyndromeDysbiosis
Interventions
DIETARY_SUPPLEMENT

Anaerobically Cultivated Human Intestinal Microbiota (ACHIM)

One vial of ACHIM suspension (ACHIM Biotherapeutics AB, Vallingby, Sweden), containing 30 x 109 colony forming unit (CFU) of bacteria, was given through the work channel of a gastroscope into the lower part of duodenum.

DIETARY_SUPPLEMENT

Donor fecal microbiota transplantation

Only 60 ml of sterile 0.9% normal saline were added to a stool specimen, collected from the respective donor, with a weight of \~30 g and homogenized manually. Then 60 ml of feces-suspension (screened from the patients view) were instilled through the work channel of a gastroscope into the lower part of the duodenum.

DIETARY_SUPPLEMENT

Placebo

Only 60 ml of sterile 0.9% normal saline were added to the patient's own stool specimen with a weight of \~30 g and homogenized manually. Then 60 ml of feces-suspension (screened from the patients view) were instilled through the work channel of a gastroscope into the lower part of the duodenum.

Trial Locations (1)

5120

Haukeland Unversity Hospital, Bergen

All Listed Sponsors
lead

Haukeland University Hospital

OTHER

NCT05088434 - Fecal Microbiota Transplantation and ACHIM for Manipulating Gut Microbiota in IBS Patients | Biotech Hunter | Biotech Hunter