Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals

NATerminatedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

September 15, 2021

Primary Completion Date

March 31, 2022

Study Completion Date

March 31, 2022

Conditions
Dental Plaque
Interventions
OTHER

Enzyme lozenge 1

Participants are instructed to take one enzyme containing lozenge three times daily, at least 30 min after a meal, for 14 days. No normal oral hygiene procedures are allowed during the intervention period.

OTHER

Enzyme lozenge 2

Participants are instructed to take one lozenge with 3x higher enzyme concentration three times daily, at least 30 min after a meal, for 14 days. No normal oral hygiene procedures are allowed during the intervention period.

OTHER

Placebo lozenge

Participants are instructed to take one placebo lozenge three times daily, at least 30 min after a meal, for 14 days. No normal oral hygiene procedures are allowed during the intervention period.

Trial Locations (1)

8000

Aarhus University, Department of Dentistry and Oral Health, Aarhus

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

University of Aarhus

OTHER

lead

Novozymes A/S

INDUSTRY

NCT05082103 - Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals | Biotech Hunter | Biotech Hunter