Comparison of the Manually Controlled Propofol Infusion and Target Controlled Infusion in Children

NACompletedINTERVENTIONAL
Enrollment

61

Participants

Timeline

Start Date

October 18, 2021

Primary Completion Date

January 17, 2022

Study Completion Date

January 24, 2022

Conditions
Propofol Anesthesia in Children
Interventions
DRUG

Propofol infusion via manually controlled pump.

Patients will receive propofol bolus 2.5-3 mg/kg, for anesthesia induction and anesthesia maintenance was continued according to the Mc Farlan scheme, meaning continuous propofol infusion is used, with gradual reduction of the infusion speed in timely manner, depending on the duration of surgery: 15mg/kg/h...13mg/kg/h...11mg/kg/h...9mg/kg/h...6mg/kg/h.

DRUG

Propofol infusion via target controlled pump.

Pedfusor model was used for delivering target controlled plasma concentration, with target concentration for anesthesia induction of 4 mcg/kg body weight and then 3 mcg/kg.

Trial Locations (1)

11000

University Children's Hospital, Belgrade

All Listed Sponsors
lead

University Children's Hospital

OTHER

NCT05081206 - Comparison of the Manually Controlled Propofol Infusion and Target Controlled Infusion in Children | Biotech Hunter | Biotech Hunter