80
Participants
Start Date
October 12, 2021
Primary Completion Date
December 16, 2021
Study Completion Date
January 13, 2022
Artemether-lumefantrine
Tablets containing 20/80 mg artemether and 120/480 mg lumefantrine will be administered according to weight as per manufacturer guidelines.
Primaquine Phosphate
The single dose of 0.25mg/kg PQ will be administered in an aqueous solution, according to a standard operating procedure (SOP) provided by the manufacturer.
Sulphadoxine-pyrimethamine with amodiaquine
Sulfadoxine/pyrimethamine tablets contain 500mg sulfadoxine and 25mg pyrimethamine. Amodiaquine tablets contain 150mg amodiaquine (as hydrochloride). Tablets will be administered according to weight as per manufacturer guidelines.
Tafenoquine
100mg tafenoquine tablets are prepared into a 1mg/mL solution in water. Solution will be given according to weight as indicated per treatment arm in 5kg bands.
Malaria Research and Training Centre, Bamako
London School of Hygiene and Tropical Medicine
OTHER