Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

PHASE3CompletedINTERVENTIONAL
Enrollment

458

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

November 1, 2022

Study Completion Date

December 1, 2022

Conditions
Actinic Keratoses
Interventions
DRUG

Test Product (A): Fluorouracil Cream, 5% topical cream

Apply cream twice daily in an amount sufficient to cover the lesions. Fluorouracil should be applied preferably with a nonmetal applicator or suitable glove. If Fluorouracil is applied with the fingers, the hands should be washed immediately afterward.

DRUG

Reference Product (B): Fluorouracil 5% Topical Cream of Mylan Pharmaceuticals Inc., Morgantown, WV 26505 U.S.A.

Apply cream twice daily in an amount sufficient to cover the lesions. Fluorouracil should be applied preferably with a nonmetal applicator or suitable glove. If Fluorouracil is applied with the fingers, the hands should be washed immediately afterward.

DRUG

Placebo Product (C): Test vehicle cream for fluorouracil 5% of Encube Ethicals Pvt. Ltd., India

Apply cream twice daily in an amount sufficient to cover the lesions. Fluorouracil should be applied preferably with a nonmetal applicator or suitable glove. If Fluorouracil is applied with the fingers, the hands should be washed immediately afterward.

Trial Locations (7)

18249

CBCC Global Research Site 007, Sugarloaf

33015

CBCC Global Research Site 001, Miami

33027

CBCC Global Research Site 003, Miramar

33175

CBCC Global Research Site 002, Miami

33308

CBCC Global Research Site 004, Lauderdale Lakes

90703

CBCC Global Research Site 006, Cerritos

93309

CBCC Global Research Site 005, Bakersfield

Sponsors
All Listed Sponsors
collaborator

CBCC Global Research

NETWORK

lead

Encube Ethicals Pvt. Ltd.

INDUSTRY

NCT05078827 - Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis | Biotech Hunter | Biotech Hunter