NCT05078047View on ClinicalTrials.gov

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

PHASE3RecruitingINTERVENTIONAL
Enrollment

646

Participants

Timeline

Start Date

March 8, 2022

Primary Completion Date

March 7, 2027

Study Completion Date

March 7, 2027

Conditions
Lung Cancer MetastaticRenal Cell CarcinomaHead and Neck CancerTriple Negative Breast CancerMerkel Cell CarcinomaHepatocellular CarcinomaMelanomaUrothelial CarcinomaColorectal Carcinoma With Microsatellite InstabilityEsophageal Squamous Cell CarcinomaEndometrial CarcinomaCervical CancerGastric/Gastro-esophageal Junction/Esophageal AdenocarcinomaBasal Cell CarcinomaSquamous Skin Carcinoma
Interventions
DRUG

Reduced dose intensity of IO

After 6 months of treatment with standard IO, IO will be administered every 3 months (at the same dose levels) until disease progression, unacceptable toxicity, death or patient's choice or investigator's decision

Trial Locations (40)

13385

WITHDRAWN

Hôpital La Timone -APHM, Marseille

14076

RECRUITING

Centre François Baclesse, Caen

21079

RECRUITING

Centre Georges François Leclerc, Dijon

25030

WITHDRAWN

CHU Besançon, Besançon

31059

RECRUITING

IUCT, Toulouse

35042

RECRUITING

Centre Eugene Marquis, Rennes

37044

RECRUITING

CHU Bretonneau, Tours

44805

RECRUITING

Institut de cancérologie de l'Ouest, Saint-Herblain

49055

RECRUITING

Institut de cancérologie de l'Ouest, Angers

51726

WITHDRAWN

Insitut Godinot, Reims

63000

RECRUITING

Centre Jean Perrin, Clermont-Ferrand

64109

RECRUITING

Centre Hospitalier de la Côte Basque, Bayonne

67200

RECRUITING

ICANS, Strasbourg

69310

RECRUITING

Hospices Civils de Lyon, Lyon

75005

WITHDRAWN

Institut Curie, Paris

75010

RECRUITING

Hôpital Saint Louis, Paris

75013

WITHDRAWN

Hôpital Pitié Salpêtrière, Paris

75015

WITHDRAWN

Hôpital Européen Georges Pompidou, Paris

84918

RECRUITING

Clinique Sainte Catherine, Avignon

86000

RECRUITING

CHU Poitiers, Poitiers

87000

RECRUITING

Clinique Chenieux, Limoges

92151

RECRUITING

Hôpital Foch, Suresnes

92210

WITHDRAWN

Institut Curie, Saint-Cloud

94010

RECRUITING

Centre Hospitalier Intercommunal, Créteil

RECRUITING

CHU Henri Mondor, Créteil

Unknown

RECRUITING

CHU Bordeaux - Hôpial Saint André, Bordeaux

NOT_YET_RECRUITING

CH Boulogne sur Mer, Boulogne-sur-Mer

NOT_YET_RECRUITING

GH Mutualiste de Grenoble, Grenoble

NOT_YET_RECRUITING

CHD Vendée, La Roche-sur-Yon

RECRUITING

Centre Oscar Lambret, Lille

RECRUITING

Centre Léon Bérard, Lyon

RECRUITING

CHU Nîmes/Institut de cancérologie du Gard, Nîmes

RECRUITING

Hôpital Cochin APHP, Paris

RECRUITING

Hôpital Saint Antoine APHP, Paris

RECRUITING

CHI Elbeuf, Saint-Aubin-lès-Elbeuf

RECRUITING

Centre Hospitalier Mémorial de Saint-Lô, Saint-Lô

RECRUITING

Clinique Mutualiste de l'Estuaire, Saint-Nazaire

RECRUITING

HIA Sainte Anne, Toulon

NOT_YET_RECRUITING

Centre Gustave Roussy, Villejuif

06189

RECRUITING

Centre Antoine Lacassagne, Nice

All Listed Sponsors
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UNICANCER

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