280
Participants
Start Date
May 31, 2022
Primary Completion Date
November 30, 2024
Study Completion Date
November 30, 2026
Reduction in the duration of antibiotic therapy 3 weeks or 6 weeks
"Drugs :~* Rifampin (IP an PO) : 10mg/Kg/12h~* Ofloxacin (PO) : 200Mg/8h~* Levofloxacin (PO) : 500mg ot 1g/ twice a day~* Ciprofloxacin : IV : 400mg/8h if Pseud spp ; 400mg/12h for others Gram-negative bacilli strains; PO : 1gr/12h if Pseud spp ; 750mg/12h for others Gram-negative bacilli strains~* Clindamycin : 600-900mg/8h~* Fusidic Acid : 500mg/8h~* Teicoplanin : 10mg/kg/12h for 5 dosis in combination, then in monotherapy.~* Ceftasidim : 2g/8h if Pseud spp ; 2g/12h for others Gram-negative bacilli strains~* Trimethoprim-sulfamethoxazole (800mg/160mg) : once per day if patient \< 80Kg ; one and a half per day if patient \> 80Kg.~* Doxycyclin : 200mg/day~* Minocyclin : 100mg/8h to 12h~* Ceftriaxon : 1g to 2g/day in IV, IM or SC~* Cefotaxim : 1g to 2g/day in IV~* Pristinamycin : 1g thrice a day"
Centre Hospitalier de Roubaix, Roubaix
Centre Hospitalier de Béthune-Beuvry, Béthune
AP-HP Ambroise Paré, Boulogne-Billancourt
Centre Hospitalier de Boulogne-sur-Mer, Boulogne-sur-Mer
Centre Hopitalier Universitaire de Brest, Brest
Centre Hospitalier Universitaire de Caen, Caen
Centre Hospitalier de Compiègne-Noyon, Compiègne
Centre Hospitalier de Dunkerque, Dunkirk
Centre Hospitalier de Lens, Lens
Centre Hospitalier Universitaire de Lille, Lille
GHICL Saint-Vincent de Paul, Lille
GHICL Saint-Philibert, Lomme
Centre Hospitalier Universitaire de Montpellier, Montpellier
Centre Hospitalier Universitaire de Nantes, Nantes
AP-HP Cochin, Paris
AP-HP Lariboisière, Paris
Centre Hospitalier Universitaire de Rouen, Rouen
Centre Hospitalier de Valenciennes, Valenciennes
Tourcoing Hospital
OTHER