The Effect of Dicloxacillin on Oral Absorption of Drugs

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

February 7, 2022

Primary Completion Date

June 22, 2022

Study Completion Date

June 22, 2022

Conditions
Healthy VolunteersDrug-drug Interaction
Interventions
DRUG

Dicloxacillin

Healthy volunteers will take 2x500 mg dicloxacillin 3 times a day for 30 days. The investigators will measure the baseline concentration of dabigatran and dicloxacillin before start of 30 days of dicloxacillin treatment. On day 9 and 27 the investigators will measure the concentration of dicloxacillin. On day 10 and 28 the investigators will measure the concentration of dabigatran.

Trial Locations (1)

5000

University of Southern Denmark, Odense

All Listed Sponsors
lead

University of Southern Denmark

OTHER