Genetic Overlap Between Anomalies and Cancer in Kids in the Children's Oncology Group: The COG GOBACK Study

Active, not recruitingOBSERVATIONAL
Enrollment

1,000

Participants

Timeline

Start Date

September 10, 2021

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2027

Conditions
Congenital AnomalyPediatric Cancer
Interventions
OTHER

Whole Genome Sequencing

Saliva collection and request for banked blood and tumor samples for sequencing

OTHER

Questionnaire Administration

Study questionnaire will include modules that collect information on maternal reproductive history, exposure to known teratogens, medical history, and previous genetic testing.

OTHER

Biospecimen collection

Saliva collection and request for banked blood and tumor samples for sequencing and biomarker analysis

OTHER

Laboratory Biomarker Analysis

Saliva collection and request for banked blood and tumor samples for biomarker analysis

Trial Locations (1)

77030

Baylor College of Medicine/ Dan L Duncan Comprehensive Cancer Center, Houston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK