Circulating Tumor Cell Reducing No-touch Nephrectomy

We aim to determine if a laparoscopic no-touch nephrectomy with an early renal pedicle ligation can decrease CTC release during surgery.

Conventional laparoscopic radical nephrectomy, which implies manipulation of the kidney, opening of the Gerota's fascia, and manipulation of peri-nephric fat during dissection, and renal pedicle isolation.

Control arm in which a laparoscopic total nephrectomy will be performed in non-cancer patients.