Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease

NARecruitingINTERVENTIONAL
Enrollment

172

Participants

Timeline

Start Date

September 29, 2022

Primary Completion Date

September 29, 2025

Study Completion Date

September 29, 2029

Conditions
Dupuytren's Disease
Interventions
PROCEDURE

Aponeurectomy with grafting

"The lipofilling is performed, once the incisions are closed and is performed with the Puregraft® system.~The fat graft is taken from the posterior, medial and anterior sides of the arm, by skin puncture. Approximately 10 cc are harvested, allowing a reinjection of about 2 cc per digital radius treated. After conditioning, the fat graft is redistributed to the curettage areas through the skin incisions."

PROCEDURE

Aponeurectomy alone

The patient is installed in dorsal decubitus position and the arm to be treated is anesthetized by axillary block. The procedure is performed in the operating room, respecting all the rules of asepsis and safety in force. A tourniquet is placed on the arm to be treated and inflated to 250mmHg. Broken incisions are then made opposite the cords to be excised, which are located by palpation. Once the noble elements have been identified, the excision of the cords and fibrous nodules can be done as completely as possible. Sometimes an arthrolysis procedure is necessary in order to restore extension to a joint that has been fixed in a flexion position for several years. Skin closure is most often possible by direct suture or by means of local fatty skin flaps. In some cases, the surgeon may use total skin grafts, or directed healing in certain areas where direct skin suture is not possible.

Trial Locations (2)

33600

RECRUITING

Institut Aquitain de la Main, Pessac

44800

RECRUITING

Santé Atlantique ELSAN, Saint-Herblain

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Elsan

OTHER