Neoadjuvant DaRT for Locally Advanced Oral Cavity SCC

NANot yet recruitingINTERVENTIONAL
Enrollment

79

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Squamous Cell CarcinomaHead and Neck Squamous Cell Carcinoma
Interventions
DEVICE

Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT

An intratumoral insertion of a seed(s), loaded with Radium-224, securely fixed in the seeds. The seeds release by recoil into the tumor short-lived alpha-emitting atoms.

Trial Locations (1)

91120

Sharett institute, Hadassah University Hospital - Ein-Kerem, Jerusalem

Sponsors
All Listed Sponsors
collaborator

European Organisation for Research and Treatment of Cancer - EORTC

NETWORK

lead

Alpha Tau Medical LTD.

INDUSTRY