Biomarker-driven Therapy for Melanoma

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

November 30, 2019

Study Completion Date

August 31, 2021

Conditions
Melanoma
Interventions
DRUG

Molecular guided therapy

Biomarker-driven therapy according to recommandations of the precision oncology tumor board including MEK Inhibitors (Trametinib 2 mg/d, Selumetinib 75 mg 2/d), MET Inhibitors (Crizotinib 250 mg 2/d, or Cabozantinib 60mg/d), RAS Inhibitor (Sorafenib 400 mg 2/d), Cell cycle Inhibitor (Palbociclib 125 mg/d) and Checkpoint Inhibitor (Nivolumab 240 mg every 2 weeks).

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Max-Planck Institut

UNKNOWN

collaborator

Alacris

UNKNOWN

lead

Charite University, Berlin, Germany

OTHER