Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function

CompletedOBSERVATIONAL
Enrollment

800

Participants

Timeline

Start Date

April 8, 2016

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Ischemic Heart DiseaseMicrovascular Coronary Artery DiseaseDiastolic DysfunctionHeart Failure With Preserved Ejection Fraction
Interventions
DIAGNOSTIC_TEST

Echocardiography

Echocardiographic grades of diastolic function was defined according to 2016 ASE/EACVI recommendations for the evaluation of LV diastolic function. Cardiac diastolic dysfunction was defined as elevated E/e'≥15.

DIAGNOSTIC_TEST

Coronary flow reserve and index of microcirculatory dysfunction

Coronary microcirculatory dysfunction was defined as having both depressed CFR (≤2.0) and elevated IMR (≥23U).

Trial Locations (4)

Unknown

University of Iowa Carver College of Medicine, Iowa City, IA, USA, Iowa City

Chonnam National University Hospital, Gwangju

Chosun University Hospital, Gwangju

Samsung Medical Center, Seoul

All Listed Sponsors
collaborator

Chonnam National University Hospital

OTHER

collaborator

Chosun University Hospital

OTHER

collaborator

Gangneung Asan Hospital

OTHER

lead

Samsung Medical Center

OTHER

NCT05058833 - Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function | Biotech Hunter | Biotech Hunter