Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

October 1, 2020

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
Barrett EsophagusEsophageal Cancer
Interventions
DEVICE

WATS-3D tissue sampling prior to forceps biopsies

WATS-3D is a brush-based tissue sampling technique. Abrasive brush sampling of large areas of the esophagus pick up cells to obtain trans-epithelial specimens. This technique samples much larger tissue areas than standard forceps biopsies. Analysis is then done by proprietary neural-network based computer scanning and molecular diagnostics to identify abnormal cells.

DEVICE

WATS-3D tissue sampling following forceps biopsies

WATS-3D is a brush-based tissue sampling technique. Abrasive brush sampling of large areas of the esophagus pick up cells to obtain trans-epithelial specimens. This technique samples much larger tissue areas than standard forceps biopsies. Analysis is then done by proprietary neural-network based computer scanning and molecular diagnostics to identify abnormal cells. This will be done after forceps biopsies in this arm.

Trial Locations (4)

60611

RECRUITING

Northwestern Memorial Hospital, Chicago

63110

NOT_YET_RECRUITING

Washington University in St. Louis, Barnes Jewish Hospital, St Louis

80045

NOT_YET_RECRUITING

University of Colorado, Aurora

90095

NOT_YET_RECRUITING

University of California, LA, Los Angeles

All Listed Sponsors
collaborator

Washington University School of Medicine

OTHER

collaborator

University of Colorado, Denver

OTHER

collaborator

University of California, Los Angeles

OTHER

lead

Northwestern University

OTHER