NCT05049226View on ClinicalTrials.gov

Third Dose Vaccination With AstraZeneca or Pfizer COVID-19 Vaccine Among Adults Received Sinovac COVID-19 Vaccine

PHASE2CompletedINTERVENTIONAL
Enrollment

1,250

Participants

Timeline

Start Date

September 24, 2021

Primary Completion Date

February 22, 2022

Study Completion Date

February 22, 2022

Conditions
COVID-19 InfectionCOVID-19 VACCINE
Interventions
BIOLOGICAL

AstraZeneca ChAdOx1 AZD1222 vaccine (AZ) full dose

"Astrazeneca COVID-19 (ChAdOx1 AZD1222) vaccine:~One dose (0.5 ml) contains: COVID-19 Vaccine (ChAdOx1-S\* recombinant) 5 × 10\^10 viral particles (vp)~\*Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike glycoprotein. Produced in genetically modified human embryonic kidney (HEK) 293 cells.~Administer: Intramuscular (IM) injection in the deltoid muscle"

BIOLOGICAL

Pfizer/BioNTech BNT162b2 vaccine (PF) full dose

"Pfizer-BioNTech COVID-19 (BNT162b2) vaccine:~Diluent: 0.9% sodium chloride (normal saline, preservative-free)~Administer: Intramuscular (IM) injection in the deltoid muscle"

BIOLOGICAL

AstraZeneca ChAdOx1 AZD1222 vaccine (AZ) half dose

"Astrazeneca COVID-19 (ChAdOx1 AZD1222) vaccine:~One dose (0.5 ml) contains: COVID-19 Vaccine (ChAdOx1-S\* recombinant) 5 × 10\^10 viral particles (vp)~\*Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike glycoprotein. Produced in genetically modified human embryonic kidney (HEK) 293 cells.~Administer: Intramuscular (IM) injection in the deltoid muscle"

BIOLOGICAL

Pfizer/BioNTech BNT162b2 vaccine (PF) half dose

"Pfizer-BioNTech COVID-19 (BNT162b2) vaccine:~Diluent: 0.9% sodium chloride (normal saline, preservative-free)~Administer: Intramuscular (IM) injection in the deltoid muscle"

Trial Locations (7)

10330

Faculty of Medicine Chulalongkorn University, Pathum Wan

10540

Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi hospital, Mahidol University, Bang Phli

10700

Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok Noi

12121

Faculty of Medicine Thammasat University, Khlong Luang

40002

Faculty of Medicine, Khon Kaen University, Khon Kaen

50200

Faculty of Medicine, Chiang Mai University, Chiang Mai

90110

Faculty of Medicine, Prince of Songkla University, Hat Yai

All Listed Sponsors
collaborator

Clinixir Co., Ltd.

UNKNOWN

collaborator

Program Management Unit-C (PMU-C), governed by Ministry of Higher Education, Science, Research and Innovation (MHESI)

UNKNOWN

lead

Mahidol University

OTHER

NCT05049226 - Third Dose Vaccination With AstraZeneca or Pfizer COVID-19 Vaccine Among Adults Received Sinovac COVID-19 Vaccine | Biotech Hunter | Biotech Hunter