NCT05042024View on ClinicalTrials.gov

Supplementation With L-ornithine But Not L-arginine Increases Density of CD68+ and CD163+ Macrophages in Periodontitis

PHASE3CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

October 20, 2017

Primary Completion Date

October 2, 2018

Study Completion Date

November 1, 2018

Conditions
Periodontitis
Interventions
PROCEDURE

Scaling and root planing

Conventional periodontal therapy, non-surgical periodontal therapy

DRUG

Oral L-arginine aspartate administration

The use of L-arginine aspartate as adjuncts to local conservative treatment (scaling and root planing) of periodontitis to optimize treatment by modulating local macrophage subpopulations

DRUG

Oral L-ornithine aspartate administration

The use of L-ornithine aspartate as adjuncts to local conservative treatment (scaling and root planing) of periodontitis to optimize treatment by modulating local macrophage subpopulations

Trial Locations (1)

36011

Ukrainian Medical Stomatological Academy, Poltava

All Listed Sponsors
lead

Ukrainian Medical Stomatological Academy

OTHER

NCT05042024 - Supplementation With L-ornithine But Not L-arginine Increases Density of CD68+ and CD163+ Macrophages in Periodontitis | Biotech Hunter | Biotech Hunter