554
Participants
Start Date
October 26, 2022
Primary Completion Date
January 31, 2027
Study Completion Date
January 31, 2027
Holbæk Obesity Treatment
"Obesity is a chronic, progressive, severe, recidivistic, and complex disease, which mandates that children and adolescents with overweight or obesity have access to a professional medical healthcare service as other pediatric chronic diseases, implying a lifelong course of treatment. The HOT method is further based on the physiological insight into the endocrine regulation of fat mass; especially on how the body adapts when it is challenged by weight loss. These insights include an understanding where the body shifts into an energy-preserving mode when the individual is initiating weight-reducing actions, such as a reduced caloric intake or an increased level of physical activity, which has numerous impacts on communication and pedagogy.~HOT is administered by healthcare nurses and dietitians at healthcare centers in Danish municipalities. Each treatment will be conducted as face-to-face sessions totalling a range of six to 12 hours for 12 months."
Conventional Obesity Treatment
"Obesity is viewed as a chronic disease that is ultimately thought to result from an imbalance between energy intake and energy expenditure. However, multiple factors, both environmental and genetic, are thought to influence the disease as well. As obesity reflects energy imbalances, the treatment plan should be designed to induce a slightly negative energy balance by focusing on diet, physical activity, and inactivity through behavior change. Taking one step at a time, will in the end lead to the same energy balance result (i.e. weight loss) and will be more sustainable for the participant whose motivation is absolutely pivotal in this process.~COT is administered by healthcare nurses and dietitians at healthcare centers in Danish municipalities. Each treatment will be conducted as face-to-face sessions totalling a range of six to 12 hours for 12 months."
RECRUITING
Municipality heath center, Solrød, Solrød Strand
RECRUITING
Municipality heath center, Ballerup, Ballerup Municipality
RECRUITING
Municipality health center, Frederikssund Kommune, Frederikssund
RECRUITING
Municipality heath center, Lejre, Lejre
RECRUITING
Municipality health center, Guldborgsund, Nykøbing Falster
Copenhagen Trial Unit, Center for Clinical Intervention Research
OTHER
University of Copenhagen
OTHER
Statens Serum Institut
OTHER
University of Florida
OTHER
Leeds Beckett University
OTHER
University of Minnesota
OTHER
Hebrew University of Jerusalem
OTHER
Frederiksberg University Hospital
OTHER
Holbaek Sygehus
OTHER