Human Immune Response to Ixodes Scapularis Tick Bites

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 28, 2022

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Tick-borne DiseasesTick ResistanceLyme Disease
Interventions
DEVICE

Xenodiagnosis Ticks

Larval ticks will be obtained from Dr. Sam Telford from a laboratory maintained tick colony at Tufts Veterinary School. These ticks are hatched from eggs laid by ticks that have fed only on specific pathogen free laboratory animals that were purchased from established vendors.

PROCEDURE

skin biopsy

2-3 mm skin punch biopsies will be performed.

PROCEDURE

blood draw

Peripheral blood draws will be performed.

Trial Locations (1)

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH