100
Participants
Start Date
May 27, 2022
Primary Completion Date
December 31, 2025
Study Completion Date
June 30, 2026
Intra-Op Prophylactic VT ablation
For surgical intra-operative ablation, efforts will be made to identify scarred myocardium based on methods such as cardiac magnetic resonance imaging, nuclear scans, and/or echocardiogram. Electrophysiological mapping may be obtained either pre-surgery or intra-operation. Mapping and ablation will be performed with the currently approved and updated mapping and ablation systems available at each center. Voltage mapping of the ventricle(s) to delineate scars will be carried out through electroanatomic mapping
Conventional Management
To ensure uniformity in control arm, a standardized AAD regimen is recommended among subjects randomized to the medical management control arm. Subjects who are already on a stable AAD regimen, such as amiodarone, sotalol or dofetilide, these should be continued
RECRUITING
Columbia University Medical Center, New York
RECRUITING
University of Rochester, Rochester
RECRUITING
UPMC, Pittsburgh
RECRUITING
University of Pennsylvania, Philadelphia
RECRUITING
Medstar Washington Hospital Center, Washington D.C.
RECRUITING
Johns Hopkins University, Baltimore
RECRUITING
Medical University of South Carolina, Charleston
RECRUITING
Piedmont Heart Institute, Atlanta
RECRUITING
Emory University, Atlanta
RECRUITING
Vanderbilt University Medical Center, Nashville
RECRUITING
Univedrsity of Louisville, Louisville
RECRUITING
Cleveland Clinic, Cleveland
RECRUITING
Ascension St. Vincent Indianapolis, Indianapolis
RECRUITING
Henry Ford Health, Detroit
RECRUITING
Houston Methodist Hospital, Houston
RECRUITING
Banner University Medical Center, Phoenix
RECRUITING
UCLA Cardiac Arrthmia Center, Los Angeles
RECRUITING
University of California San Francisco, San Francisco
RECRUITING
Tufts Medical Center, Boston
National Heart, Lung, and Blood Institute (NHLBI)
NIH
University of Rochester
OTHER